Stephen Senn

Latest publications

Contribution to the discussion of '"A critical evaluation of the current p-value controversy"'.

  • Competence Center for Methodology and Statistics
September 01, 2017
2017 Sep. Biom J.59(5):892-894. Epub 2017 Apr 27.
By:
  • Senn S.

Statistical issues in first-in-human studies on BIA 10-2474: Neglected comparison of protocol against practice.

  • Competence Center for Methodology and Statistics
March 01, 2017
2017 Mar. Pharm Stat.16(2):100-106. Epub 2017 Feb 16.
By:
  • Bird SM
  • Bailey RA
  • Grieve AP
  • Senn S.

Sample size considerations for n-of-1 trials.

  • Competence Center for Methodology and Statistics
January 01, 2017
2017 Jan. Stat Methods Med Res.962280217726801. [Epub ahead of print].
By:
  • Senn S.

Defining drug response for stratified medicine.

  • Competence Center for Methodology and Statistics
January 01, 2017
2017 Jan. Drug Discov Today.22(1):173-179. Epub 2016 Nov 3.
By:
  • Lonergan M
  • Senn SJ
  • McNamee C
  • Daly AK
  • Sutton R
  • Hattersley A
  • Pearson E
  • Pirmohamed M.

Understanding variation in sets of N-of-1 trials.

  • Competence Center for Methodology and Statistics
December 01, 2016
2016 Dec. PloS One.11(12):e0167167.
By:
  • Araujo A
  • Julious S
  • Senn S.

Reporting of cross-over clinical trials of analgesic treatments for chronic pain: Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks systematic review and recommendations.

  • Competence Center for Methodology and Statistics
November 01, 2016
2016 Nov. Pain.157(11):2544-2551.
By:
  • Gewandter JS
  • McDermott MP
  • McKeown A
  • Hoang K
  • Iwan K
  • Kralovic S
  • Rothstein D
  • Gilron I
  • Katz NP
  • Raja SN
  • Senn S
  • Smith SM
  • Turk DC
  • Dworkin RH.

A chronicle of permutation statistical methods: 1920–2000, and beyond, by K J Berry, J E Johnston, and P J W Mielke.

  • Competence Center for Methodology and Statistics
May 31, 2016
2016 May. BSHM Bull.31(2):155-156.
By:
  • Senn S.

Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations.

  • Competence Center for Methodology and Statistics
May 21, 2016
2016 May. Eur J Epidemiol.31(4):337-50. Epub 2016 May 21.
By:
  • Greenland S
  • Senn SJ
  • Rothman KJ
  • Carlin JB
  • Poole C
  • Goodman SN
  • Altman DG.

Mastering variation: variance components and personalised medicine.

  • Competence Center for Methodology and Statistics
March 30, 2016
2016 Mar. Stat Med.35(7):966-77. Epub 2015 Sep 28.
By:
  • Senn S.

Various varying variances: The challenge of nuisance parameters to the practising biostatistician.

  • Competence Center for Methodology and Statistics
August 01, 2015
2015 Aug. Stat Methods Med Res.24(4):403-19. Epub 2014 Feb 2.
By:
  • Senn S.

Individual response to exercise training - a statistical perspective.

  • Sports Medicine Research Laboratory
  • Competence Center for Methodology and Statistics
June 15, 2015
2015 Jun. J Appl Physiol.118(12):1450-9. Epub 2015 Feb 5.
By:
  • Hecksteden A
  • Kraushaar J
  • Scharhag-Rosenberger F
  • Theisen D
  • Senn S
  • Meyer T.

Progression-seeking bias and rational optimism in research and development.

  • Competence Center for Methodology and Statistics
March 01, 2015
2015 Mar. Nat Rev Drug Discov.14(3):219-21. Epub 2015 Feb 6.
By:
  • Lendrem DW
  • Lendrem BC
  • Peck RW
  • Senn SC
  • Day S
  • Isaacs JD.

R&D productivity rides again?

  • Competence Center for Methodology and Statistics
January 01, 2015
2015 Jan. Pharm Stat.14(1):1-3. Epub 2014 Oct 22.
By:
  • Lendrem D
  • Senn SJ
  • Lendrem BC
  • Isaacs JD.

A note regarding meta-analysis of sequential trials with stopping for efficacy.

  • Competence Center for Methodology and Statistics
November 01, 2014
2014 Nov. Pharm Stat.13(6):371-5. Epub 2014 Oct 9.
By:
  • Senn S.

A note regarding Lee's checks for minimum numbers of subjects where relative risks have been calculated.

  • Competence Center for Methodology and Statistics
October 15, 2014
2014 Oct. Stat Med.33(23):4135-8.
By:
  • Senn S
  • Jude-Eze EN.

Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations.

  • Competence Center for Methodology and Statistics
September 01, 2014
2014 Sep. Pain.155(9):1683-1695. Epub 2014 May 24.
By:
  • Gewandter JS
  • Dworkin RH
  • Turk DC
  • McDermott MP
  • Baron R
  • Gastonguay MR
  • Gilron I
  • Katz NP
  • Mehta C
  • Raja SN
  • Senn S
  • Taylor C
  • Cowan P
  • Desjardins P
  • Dimitrova R
  • Dionne R
  • Farrar JT
  • Hewitt DJ
  • Iyengar S
  • Jay GW
  • Kalso E
  • Kerns RD
  • Leff R
  • Leong M
  • Petersen KL
  • Ravina BM
  • Rauschkolb C
  • Rice AS
  • Rowbotham MC
  • Sampaio C
  • Sindrup SH
  • Stauffer JW
  • Steigerwald I
  • Stewart J
  • Tobias J
  • Treede RD
  • Wallace M
  • White RE.

A note regarding 'random effects'.

  • Competence Center for Methodology and Statistics
July 20, 2014
2014 Jul. Stat Med.33(16):2876-2877.
By:
  • Senn S.

Drug development: EU paediatric legislation, the European Medicines Agency and its Paediatric Committee-adolescents' melanoma as a paradigm.

  • Competence Center for Methodology and Statistics
July 01, 2014
2014 Jul. Pharm Stat.13(4):211-3. Epub 2014 Jun 6.
By:
  • Rose K
  • Senn S.

Authors are also reviewers: problems in assigning cause for missing negative studies [v1; ref status: indexed, http://f1000r.es/uo].

  • Competence Center for Methodology and Statistics
December 25, 2013
2013 Dec. F1000Res.2:17.
By:
  • Senn S.

Bad karma.

  • Competence Center for Methodology and Statistics
December 01, 2013
2013 Dec. Med Writ.22(4):252-255.
By:
  • Senn S.